Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-includes/pomo/plural-forms.php on line 210 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 1231 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 1268 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 1272 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 1297 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 3026 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 3033 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 3046 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/common.php on line 3525 Deprecated: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gravityforms/includes/fields/class-gf-field-multiselect.php on line 221 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/codestyling-localization/includes/idna_convert.class.php on line 421 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/codestyling-localization/includes/idna_convert.class.php on line 435 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/codestyling-localization/includes/idna_convert.class.php on line 826 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/codestyling-localization/includes/idna_convert.class.php on line 957 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; ES_Text_Diff_Renderer has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/exploit-scanner/exploit-scanner.php on line 959 Deprecated: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gotmls/index.php on line 13 Deprecated: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/gotmls/images/index.php on line 188 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/twitter/widget.php on line 234 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mtheme_SidebarGallery_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/sidebar-gallery.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/sidebar-gallery.php on line 444 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mtheme_Recent_Posts has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/recent.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/recent.php on line 153 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mtheme_Popular_Posts has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/popular.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/popular.php on line 155 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mtheme_Social_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/social.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/social.php on line 242 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mTheme_Widget_Flickr has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/flickr.php on line 3 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/flickr.php on line 68 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mTheme_Address_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/address.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/address.php on line 118 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mTheme_Video_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/video.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/video.php on line 59 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mTheme_Portfolio_Related_List_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/portfolio-related-list.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/portfolio-related-list.php on line 126 Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; mTheme_Portfolio_Type_List_Widget has a deprecated constructor in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/portfolio-type.php on line 2 Deprecated: Function create_function() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/imaginem-widgets/widgets/portfolio-type.php on line 68 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/paid-memberships-pro/includes/lib/name-parser.php on line 28 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/paid-memberships-pro/includes/lib/name-parser.php on line 134 Warning: session_start(): Cannot start session when headers already sent in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/popup-with-fancybox/popup-with-fancybox.php on line 34 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 156 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 156 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 209 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 210 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 211 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 216 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 217 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 218 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 219 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 264 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 287 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 292 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 298 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 308 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 309 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 319 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 320 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 321 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 331 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 332 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 333 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 334 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 344 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 345 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 346 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 347 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 348 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 523 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 553 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 566 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 613 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 652 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 694 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 694 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 696 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 699 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 708 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 714 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 719 Deprecated: Array and string offset access syntax with curly braces is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-content/plugins/wordpress-popup/vendor/campaignmonitor/createsend-php/class/services_json.php on line 725 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/load.php on line 651 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Notice: Trying to access array offset on value of type bool in /customers/b/c/0/norvect.no/httpd.www/wp-includes/theme.php on line 2240 Notice: The called constructor method for WP_Widget in mtheme_SidebarGallery_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mtheme_Recent_Posts is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mtheme_Popular_Posts is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mtheme_Social_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mTheme_Widget_Flickr is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mTheme_Address_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mTheme_Video_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mTheme_Portfolio_Related_List_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Notice: The called constructor method for WP_Widget in mTheme_Portfolio_Type_List_Widget is deprecated since version 4.3.0! Use
__construct()
instead. in /customers/b/c/0/norvect.no/httpd.www/wp-includes/functions.php on line 3902 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 New research from Prof. Zhang on persister drugs - NorVect Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 503 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 503 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 506 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 506 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 509 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 509 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 512 Notice: Trying to access array offset on value of type null in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/functions.php on line 512 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358
Notice: Trying to access array offset on value of type bool in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/framework/functions/framework-functions.php on line 540
Menu
Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 2425

New research from Prof. Zhang on persister drugs

Notice: Trying to access array offset on value of type bool in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/framework/functions/framework-functions.php on line 635

Ying Zhang Ph.D, MD, who spoke at the NorVect conference this past weekend has published very interesting new research today in the journal “Emerging Microbes & Infections”.

Ying Zhang

BACKGROUND:
Several studies (incl. animal models) have indicated the continued presence of B. burgdorferi in some form and suggest that current Lyme treatment may not be sufficient to eliminate B. burgdorferi persisters, or that the immune system fails to clear persisting organisms or bacterial debris, which may be underlying causes for those who suffer from non-resolving symptoms of Lyme disease. To date, there is currently no effective antibiotic treatment or preventative strategy for those who suffer from persistent symptoms after Lyme disease.

Consistent with the difficulty to eradicate B. burgdorferi in animal models, B. burgdorferi develops various morphological variant forms, such as round bodies and microcolonies, that are refractory or resistant to antibiotics and stresses. For example, it has been demonstrated that whereas the frontline drugs, such as doxycycline and amoxicillin, kill or inhibit the growing spirochetal form of B. burgdorferi effectively, they have little activity in killing non-growing persisters that are enriched in the stationary phase or microcolonies or as biofilm-like aggregates of B. burgdorferi. There is significant interest in the identification of drugs that target B. burgdorferi persisters.

SUMMARY AND FINDINGS:
Zhang’s research team set out to identify drugs that can more effectively kill B. burgdorferi persisters, and has recently developed a new viability assay using SYBR Green I/propidium iodide (PI) dyes, which allowed them to screen FDA-approved drug library against stationary phase B. burgdorferi persisters. Using this high-throughput assay, they identified a number of drug candidates, such as daptomycin, clofazimine, cefoperazone, and carbomycin that have excellent activity against in vitro B. burgdorferi persisters.

You can read the whole article here

Notice: Trying to access array offset on value of type bool in /customers/b/c/0/norvect.no/httpd.www/wp-content/themes/ideas/framework/functions/framework-functions.php on line 540
Notice: compact(): Undefined variable: limits in /customers/b/c/0/norvect.no/httpd.www/wp-includes/class-wp-comment-query.php on line 853 Notice: compact(): Undefined variable: groupby in /customers/b/c/0/norvect.no/httpd.www/wp-includes/class-wp-comment-query.php on line 853
Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358 Deprecated: Function get_magic_quotes_gpc() is deprecated in /customers/b/c/0/norvect.no/httpd.www/wp-includes/formatting.php on line 4358