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Tag : tick borne diseases

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A new article on Bartonella and possible treatments:

“Pathogenicity and treatment of Bartonella infections”
By Emmanouil Angelakis, Didier Raoult
International Journal of Antimicrobial Agents, May 9th 2014.

Abstract
Bartonella spp. are responsible for emerging and re-emerging diseases around the world. The majority of human infections are caused by Bartonella henselae, Bartonella quintana and Bartonella bacilliformis, although other Bartonella spp. have also been associated with clinical manifestations in humans. The severity of Bartonella infection correlates with the patient’s immune status. Clinical manifestations can range from benign and self-limited to severe and life-threatening disease. Clinical conditions associated with Bartonella spp. include local lymphadenopathy, bacteraemia, endocarditis, and tissue colonisation resulting in bacillary angiomatosis and peliosis hepatis. Without treatment, Bartonella infection can cause high mortality. To date, no single treatment is effective for all Bartonella-associated diseases. In the absence of systematic reviews, treatment decisions for Bartonella infections are based on case reports that test a limited number of patients. Antibiotics do not significantly affect the cure rate in patients with Bartonella lymphadenopathy. Patients with Bartonella spp. bacteraemia should be treated with gentamicin and doxycycline, but chloramphenicol has been proposed for the treatment of B. bacilliformis bacteraemia. Gentamicin in combination with doxycycline is considered the best treatment regimen for endocarditis, and erythromycin is the first-line antibiotic therapy for the treatment of angioproliferative lesions. Rifampicin or streptomycin can be used to treat verruga peruana. In this review, we present recent data and recommendations related to the treatment of Bartonella infections based on the pathogenicity of Bartonella spp.

http://www.sciencedirect.com/science/article/pii/S0924857914001186

International conference on vector-borne diseases – first and biggest of its kind in Scandinavia

Norvect Conference Program

Program Monday May 26th 2014

7.45 am – 9.00 am

Registration

9.00 am – 9.10 am

Welcome by NorVect

Trine Skei Grande (Liberal Party, Venstre) gives opening speech

9.10 am – 10.10 am

Joseph J. Burrascano Jr. MD
Lyme Borreliosis – History, Clinical Presentations, Testing and Diagnosis (incl. 5-10 minutes Q&A)

10.10 am – 11.05 am

Jyotsna Shah, Ph.D, CCLD, MBA
What Have We Learnt About Diagnosis of Lyme and Other Tick-borne Diseases in The Last 20 Years? (incl. 5-10 minutes Q&A)

11.05 am– 11.25 am

Break

11.25 am– 12.35am

Richard I. Horowitz, MD
Tick-borne Co-infections: Presentation, Diagnosis and Treatment. (incl. 5-10 minutes Q&A)

12.35 pm– 1.35 pm

Lunch – networking, knowledge sharing

1.35 pm – 2.35 pm

Christian Perrone, PhD, MD
The gap between current diagnostic tests for Lyme disease and associated diseases and the diversity of pathogens isolated in the world.(incl. 5- 10 minutes Q&A)

2.35 pm – 3.05 pm

Carl Morten Motzfeldt Laane, PhD
Easy Detection of Bacteria and Parasites in Infected Human Blood by Microscopy. Some Simple, Low-cost Methods. (incl. 5 minutes Q&A)

3.05 pm – 2.30 pm

Bela Bózsik, MD
DualDur®reagent & method in diagnosis & pathogenesis for TBD – 30 years practice (incl. 5 minutes Q&A)

3.25 pm – 3.45 pm

Break

3.45 pm – 4.25 pm

Alan MacDonald, MD
Borrelia -diverse Morphologies in culture and in Human Infections (incl 10 minutes Q&A)

4.25 pm– 4.45 pm

Armin Schwarzbach, Ph.D, MD
Borrelia-Elispot: A Game-Changer in diagnostics?

4.45 pm– 5.30 pm

Dialogue/ Panel discussions

Program Tuesday May 27th 2014

07.30 – 08.30 am

Registration

08.30 – 09.30 am

Joseph J. Burrascano Jr. MD
Lyme Borreliosis: Treatment and Case Histories (incl.10 minutes Q&A)

09.30 – 11.15 am

Richard I. Horowitz, MD
Why Can´t I Get Better? Using the Lyme-MSIDS Map in Chronic Illness. (incl. 10-15 minutes Q&A)

11.15 – 11.30 am

Break

11.30 am – 12.30 pm

Dr. Edward B. Breitschwerdt, DVM
Bartonellosis: A One Health Approach to An Emerging Infectious Disease (incl. 10 minutes Q&A)

12.30 pm – 1.30 pm

Lunch – networking, knowledge sharing

1.30 pm – 1.55 pm

Åshild Andreassen, Ph.D
ScandTick – Regional cooperation against tick-borne diseases. (incl. 5 minutes Q&A)

1.55 pm – 2.45 pm

Eva Sapi, Ph.D
Biofilms and antibiotic resistance of Borrelia burgdorferi (incl. 5-10 minutes Q&A)

2.45 pm – 3.25 pm

Alan MacDonald, MD
Human Borrelia Deaths, Autospy studies, and Chronic Morbidities (incl. 10 minutes Q&A).

3.25 pm– 3.40 pm

Break

3.40 pm – 4.30 pm

Judith Miklossy, Ph.D, MD, DSc
Chronic Lyme disease and Lyme dementia (incl. 5-10 minutes Q&A)

4.30 pm – 4.50 pm

Randi Eikeland, Ph.D, MD
European Neuroborreliosis Long-term Follow-up

4.50 pm – 5.30 pm

Dialogue/ Panel discussion

 

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